Long-term neurologic outcomes of COVID-19. COVID-19…

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Long-term neurologic outcomes of COVID-19. COVID-19 infection has been linked to a range of lasting neurological and psychological disorders, including depression, memory problems, and Parkinson’s-like disorders, within the first year following infection.

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  1. “We estimated that the hazard ratio of any neurologic sequela was 1.42 (95% confidence intervals 1.38, 1.47) and burden 70.69 (95% confidence intervals 63.54, 78.01) per 1,000 persons at 12 months. The risks and burdens were elevated even in people who did not require hospitalization during acute COVID-19.” (From Abstract)

    So… tell me if I have this wrong: they find that about 7% of people who get COVID end up with identifiable neurological issues, which is 1.4 times the rate that happens in non-covid patients

    Edit: Be sure to read (and VOTE UP!) justgetoffmylawn’s correction below – that the 7% is an increase in rates above baseline…. an additional 70 people per 1,000

  2. Here’s a good summary of the study, from the university where it was conducted – [https://medicine.wustl.edu/news/covid-19-infections-increase-risk-of-long-term-brain-problems/](https://medicine.wustl.edu/news/covid-19-infections-increase-risk-of-long-term-brain-problems/)

    Overall, extremely well-designed study. The biggest limitation is that the data was collected before vaccines were available, and obviously during earlier variants, so we can’t know exactly how this generalizes to the present… but it’s definitely concerning nonetheless.

  3. For people saying it’s other things going on in the world causing neurological disorders, please click on the link. Also see below – neurological disorders is not limited to people getting depressed at the state of the world.

    The whole point of these studies is to compare different populations. Here they compared *people who got Covid vs people who didn’t get Covid*. All would’ve been subject to similar events in the world, lockdowns, etc. Not saying those things don’t cause problems, but this is one specific study.

    This shows an [increase of 42% in various neurological and and psychological disorders](https://www.nature.com/articles/s41591-022-02001-z#:~:text=Our%20results%20show,intervals%201.38%2C%201.47) in the year following Covid infection. So that’s for just one year. Could be more after a year, could level off.

    For those who won’t click on the link, here are some of the neurological disorders where they found elevated risks.

    >neurologic sequelae including ischemic and hemorrhagic stroke, cognition and memory disorders, peripheral nervous system disorders, episodic disorders (for example, migraine and seizures), extrapyramidal and movement disorders, mental health disorders, musculoskeletal disorders, sensory disorders, Guillain–Barré syndrome, and encephalitis or encephalopathy

    Limitations of the study are that it’s in a mostly male population that skews a bit older. Some similar results have been found in other studies, but rates may differ among different cohorts.

  4. What I am curious to know is whether other common viruses that have been in circulation in society (like the flu) can also be linked to similar effects? If we had the same number of infections for the flu as we have for coronavirus-19, then would we possibly see a similar trend?

    In other words, is this a coronavirus-19 specific effect or does it apply to other viruses as well?

  5. This is so important. I wish they would look into other virulent diseases like the infection with the Eppstein Barr virus and it’s connection to, for example, depression as well.

    If you consider that studies have shown that medication like Ibuprofen works against symptoms of depression the theories around long term psychological/neurological effects of infections seem to solidify.